One woman is in a “moderate to serious” condition and four others are in a “moderate condition”, the ambulance service said.
They have been taken to the nearby Soroka Hospital.
Shortly after the attack, Israel’s transport minister Miri Regev called for the families of “terrorists” to be deported from the country.
“The time has come for a deterrent punishment to prevent the attacks on Israeli territory,” she wrote on X.
Last week, seven people were killed in a shooting and knife attack in Tel Aviv after a gunman opened fire at members of the public in the Jaffa area.
Israeli authorities have said they are on high alert across the country ahead of the one year anniversary of Hamas’s assault on southern Israel on 7 October last year, which triggered the current Gaza war.
