Boeing workers voted to strike on September 13 after rejecting a new contract deal, which included a 25% pay rise over four years.
The union had initially aimed for a number of improvements to workers’ packages, including a 40% pay rise.
Almost 95% of the union members – who produce planes including the 737 Max and 777 – voted to reject Boeing’s initial offer.
Of those who voted, 96% backed strike action until a new agreement could be reached.
The strike threatens to cost Boeing billions of dollars, deepening the crisis at a company already facing significant challenges.
Its impacts are already being felt across the industry and wider US economy too, as Boeing has halted shipments of most parts and taken other steps to save money.
The company has already suspended the jobs of tens of thousands of staff.
It has also said that US-based executives, managers and staff would be asked to take one week of furlough every four weeks for as long as the walkout lasts.
Government officials are now helping to mediate talks between the two sides.